POLYMYXIN B for Injection, USP

LATEX-FREE • PRESERVATIVE-FREE • AP RATED

Brand Name Equivalent: Polymyxin B for Injection, USP	Electronic Catalog
Therapeutic Category: Anti-infective / Antibiotic

Consider these SAGENT Benefits:
• Available in 500,000 units per vial
• LATEX-FREE
• Preservative-free
• Discover PreventIV Measures^SM packaging features:
- Easy-to-read drug name and dosage strength
- Bar codes included on the vial and carton for ease of scanning
- Unique label design to help product stand out on the shelf
• Enhanced packaging and labeling designed to promote safety and help reduce medication errors

NDC #25021	Description	Strength	Fill Volume	Concentration	Container Size	Closure	Unit of Sale	Package Insert	Storage Requirements	Product Photos	360^o View
117-10	Glass Vial	500,000 units	N/A	N/A	10 mL	20 mm	10

Polymyxin B Catalog Insert MSDS Sheet Bar Codes Wholesaler Item Numbers

WARNINGS:
CAUTION: WHEN THIS DRUG IS GIVEN INTRAMUSCULARLY AND/OR INTRATHECALLY, IT SHOULD BE GIVEN ONLY TO HOSPITALIZED PATIENTS, SO AS TO PROVIDE CONSTANT SUPERVISION BY A PHYSICIAN.
RENAL FUNCTION SHOULD BE CAREFULLY DETERMINED AND PATIENTS WITH RENAL DAMAGE AND NITROGEN RETENTION SHOULD HAVE REDUCED DOSAGE. PATIENTS WITH NEPHROTOXICITY DUE TO POLYMYXIN B SULFATE USUALLY SHOW ALBUMINURIA, CELLULAR CASTS, AND AZOTEMIA. DIMINISHING URINE OUTPUT AND A RISING BUN ARE INDICATIONS FOR DISCONTINUING THERAPY WITH THIS DRUG.
NEUROTOXIC REACTIONS MAY BE MANIFESTED BY IRRITABILITY, WEAKNESS, DROWSINESS, ATAXIA, PERIORAL PARESTHESIA, NUMBNESS OF THE EXTREMITIES, AND BLURRING OF VISION. THESE ARE USUALLY ASSOCIATED WITH HIGH SERUM LEVELS FOUND IN PATIENTS WITH IMPAIRED RENAL FUNCTION AND/OR NEPHROTOXICITY.
THE CONCURRENT OR SEQUENTIAL USE OF OTHER NEUROTOXIC AND/ OR NEPHROTOXIC DRUGS WITH POLYMYXIN B SULFATE, PARTICULARLY BACITRACIN, STREPTOMYCIN, NEOMYCIN, KANAMYCIN, GENTAMICIN, TOBRAMYCIN, AMIKACIN, CEPHALORIDINE, PAROMOMYCIN, VIOMYCIN, AND COLISTIN SHOULD BE AVOIDED.
THE NEUROTOXICITY OF POLYMYXIN B SULFATE CAN RESULT IN RESPIRATORY PARALYSIS FROM NEUROMUSCULAR BLOCKADE, ESPECIALLY WHEN THE DRUG IS GIVEN SOON AFTER ANESTHESIA AND/OR MUSCLE RELAXANTS.
USAGE IN PREGNANCY: THE SAFETY OF THIS DRUG IN HUMAN PREGNANCY HAS NOT BEEN ESTABLISHED.

Please refer to full prescribing information.
[Back to Products page]	LATEX-FREE = There is no natural rubber latex in the vial container closure or in the label adhesive in this SAGENT product. This product information is intended for U.S. residents only. All trademarks and registered trademarks are the property of their respective owners.